Based on the well-established Capto base matrix and with traditional ionic group ligands, they provide many opportunities for improved productivity and straightforward process development. The ability to run at higher flow rates and higher bed heights also increases flexibility in process design.Ĭapto SP ImpRes and Capto Q ImpRes are BioProcess™ chromatography media developed for large-scale purification of biopharmaceutical proteins. Alternatively, you can purchase each packing component separately, so that. To fill the empty column, you can use Tricorn Packing Equipment, which is a complete column packing set-up. In this work, we evaluated this resin using Cytivas Capto MMC ImpRes, a well-established mixed-mode resin with similar properties, as a benchmark. Both chromatography media (resins) are part of an expanded high-resolution platform based on the high-flow agarose Capto product line.īy combining the high-flow characteristics of Capto media with a small particle size, Capto SP ImpRes and Capto Q ImpRes deliver excellent pressure-flow properties with impressive resolution. The table below lists the main resin properties. Perform chromatography optimization and robustness studies in columns packed with SP Sepharose FF and Capto SP ImpRes resins Packing the Tricorn empty columns. Table 1: Dynamic binding capacities for WorkBeads 40 S and Capto SP ImpRes. HiScreen Capto SP ImpRes column is packed with strong cation exchange modern resin for fast high resolution protein purification in process development.Chromatography columns separate molecules within mixtures during gas or liquid chromatography. 8 µm Q Strong anion 2 to 12 BSA 50 mg/mL resin Tricorn glass column Capto HiRes Q 5/50 1 mL 5 × 50 0.5 to 2. Datasheet: Capto™ SP ImpRes Capto Q ImpResĬapto SP ImpRes and Capto Q ImpRes are strong cation and strong anion exchangers for the high-throughput intermediate purification and polishing steps of a wide range of biomolecules. This resin has optimal flow-pressure properties and is stable towards. Capto SP ImpRes Capto SP ImpRes Capto S ImpAct mAb separation Cation exchanger Anion Anion exchanger Capto S Capto Capto DEAE Capto XP PreDictor Screening plates.
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